Liposomal Formula VITAMIN D3 2500IU is a dietary supplement containing 2500 units of vitamin D3 (as cholecalciferol) which helps maintain normal blood calcium levels and normal bone condition.

Liposomal shaping technology results in greater absorption and
bioavailability of active substances and vitamins.

The liposomes

Liposomes belong to the colloidal dispersion of transport systems of bioactive molecules which have the ability to transport them, improving their efficiency. The dimensions of the liposomes depending on the method of their preparation and the physicochemical characteristics of their structural units are in the order of nanometers up to the order of a few micrometers.

Historically, in the early 1960s, there was a tendency to study the biophysical properties of colloidal systems which had lipid and phospholipid composition, with the aim of understanding the biophysical functions of cells. The biophysicist A.D. Bangham studied lipid colloidal dispersions to simulate cell membranes and study their functionality.

Liposomes, since they are made from building materials such as those of our cells, have advantages that are related to the 'friendliness' of human tissues. They have the ability to transport lipophilic bioactive molecules that do not dissolve easily in aqueous media and therefore have absorption and bioavailability problems, eg vitamins, curcumin, etc. but also water-soluble or amphiphilic molecules, improve their dissolution rate and absorption. through the gastrointestinal tract.

Liposomes can transport bioactive substances and improve their penetration through the gastrointestinal tract and are effective 'vehicles' for transporting bioactive molecules.

Liposomal technology and especially the innovative technology of supramolecular phospholipid complexes with lipid bilayer structure can improve the therapeutic efficacy of dietary supplements and are an innovation in this field, giving high added value to the final dosage form.

The text was created in collaboration with the Laboratory of Pharmaceutical Nanotechnology of the Department of Pharmacy of the National and Kapodistrian University of Athens
Bibliography: (1) K. Demetzos. ‘Pharmaceutical Nanotechnology. Basic Principles and Practical Applications ’, Ed. Parisianou, 2014 (2) Y. Perrie, T. Rades ‘Pharmaceutical Technology-Transportation and targeted action of drugs’, Scientific Supervision K. Demetzos, Ed. Parisianou, 2016.

EOF Notification Number: 42630 / 11-05-2021
(The Notification Number to the EOF is not a marketing authorization from the EOF)